Jingtian Zhou

About Me

I’m starting my lab in January 2024 at the Arc Institute, a new research institute operating in partnership with Stanford University, UCSF, and UC Berkeley.

Before joining Arc, I was a Ph.D. students in Joseph Ecker’s laboratory at the Salk Institute and Howard Hughes Medical Institute. I received my B.S. from Tsinghua University and my Ph.D. through the Bioinformatics and Systems Biology program at the University of California, San Diego. My research have focused on exploring the gene regulation landscape of the mammalian brain through integrative analyses of multimodality single-cell data. At Arc, I will continue to develop single-cell high-throughput technologies and computational tools in my own lab, to come up with more diverse types of data and analyses for quantitative modeling of gene expression dynamics.

Research Interests

• Single Cell Genomics
• Sequence to Phenotype
• Gene Regulation in Development

News

• [Dec. 2023] Our paper linking molecular cell types with neural projections across the whole mouse brain is published in Nature!
• [Dec. 2023] Our paper about whole mouse brain DNA methylation and 3D genome atlas is published in Nature!
• [Oct. 2023] Our paper about adult human brain DNA methylation and 3D genome atlas is published in Science!

Key Publications

Whole Mouse Brain

Single-cell DNA methylation and multi-modality integrative atlas of whole mouse brain and association with neuronal connectivity.

3D Genome Structure

Experimental technologies, computational tools, and large dataset analyses of single-cell 3D genome.

Undergraduate Work

Network analyses and deep learning frameworks for modeling gene regulation.

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